Simplicity, clarity, complexity, and ambiguity are not mutually exclusive states in language; the sensitive typographer is one who can manifest these states in the right mix by controlling the elements at his or her disposal.

Timothy Samara, Making or Breaking the Grid

A grid…is designed in response to the internal pressures of content (text, image, data) and the outer edge or frame (page, screen, window).” 

Ellen Lupton, Thinking With Type